August 15, 2012…Type 2 diabetes is an epidemic in the US and around the world. Over 26 million people in the US have type 2 diabetes, and countless others are on the road to diabetes with pre diabetes. (80 million people in the US have pre diabetes). Of these millions of people with diabetes, 84% take medication for the disease. Diabetes costs exceed 174 billion dollars/year.
Having type 2 diabetes automatically increases your risk of developing cancer. Breast, colon, prostate, pancreatic, ovarian, and skin cancers are already directly linked to diabetes. And now in the news, a commonly prescribed diabetes drug…Actos….is implicated in increasing the risk of cancer bladder by 2-3 times! And even with this discovery, Actos remains on the market and is prescribed daily.
Let’s took a look at how Actos evolved. I think you might be shocked that of the 3 drugs introduced since the late 1990’s in the class of Actos, two have been removed from the market for serious health concerns. You may recall the diabetes drug Rezulin. Rezulin was promoted as the “ drug of the future” because it was considered multi-functional: it helped decrease blood sugar by increasing release of insulin, it helped decrease liver release of glycogen that raised the blood sugar, and it improved insulin sensitivity by decreasing fat cell size and improving the connection of insulin to the fat and muscle cells. The problem with Rezulin? It was found to promote severe liver toxicity. Although this serious and potentially deadly side effect was reported in 1997, but the drug was not removed from the market until 2000.
A year after Rezulin was released, two other sister compounds found their way to the US market: Actos and Avandia. The FDA may have been forced to remove Rezulin but it allowed Actos and Avandia to remain. They indicated that Rezulin was more toxic to the liver than the other two drugs.
Fast forward to 2010…. There remain contraindications to the use of Avandia and Actos: toxicity and heart attack/stroke. These drugs can cause a significant increase in fluid retention and thereby increase the risk of heart failure by about 70%.
On September 23, 2010, the U.S. Food and Drug Administration (FDA) announced that it would significantly restrict the use of the diabetes drug Avandia. This was in response to data that suggested an elevated risk of cardiovascular events, such as heart attack and stroke.
Two TZD “family”drugs down and one to go …..the lone ranger of TZD medications remains Actos. For years it was promoted as being less dangerous than Avandia….with less fluid retention and a lesser chance of liver toxicity.
But a few years ago….the negative buzz began. And this time, the possible side effect was especially troublesome:
Actos was linked to a significantly increased risk for bladder cancer. A 2-3 times increase of the risk for bladder cancer is very significant. This is on top of an increased risk for heart attack/stroke/and liver toxicity.
And yet, Actos remains on the market. Several European countries have yanked Actos from their shelves, but not the US. Your MD may prescribe Actos today.
Here is my point. Drugs are being rushed to the market without enough long term testing. I have been involved in the medical field for over 30 years and I never remember this “here today, gone tomorrow” mentality when it comes to prescription medication. There is a mad rush to get these drugs to market because the treatment of diabetes is a billion + annual dollar industry. Even if a small portion of the potential market is harnessed into using a medication, there is BIG money to be made.
I will conclude by noting this:
The “drugs of the future” that are all leaving the market one by one were able to do 3 things:
1. Decrease blood sugar by increasing the amount of insulin produced by the pancreas to manage high blood sugar readings
2. Decrease the liver’s release of glycogen during the night while you sleep and between meals that exceed 5 hours without eating.
3. Decrease the size of fat cells that would improve insulin sensitivity and decrease insulin resistance.
The following is a big deal. I’m not so sure the major medical associations or the pharmaceutical industry wants you to know this. There is a lifestyle program that accomplishes EVERYTHING the TZD medications accomplish…without the TZD. Without the potential deadly side effects. Without increasing the progression of diabetes to require more and more medications and higher doses of medications.
The program is called: The Metabolism Miracle. Read about it at http://www.themetabolismmiracle.com and http://www.thediabetesmiracle.com. There is one book that can give you the entire program for under 12.00. There is also an online support site that links you directly with the author of the program….the author is on site daily and personally answers your questions at http://www.Miracle-Ville.com. The cost of Miracle-Ville, if you choose to join …is 4 dollars per MONTH. So…for a total of 60.00 per YEAR (the book and support site combined)…you would have excellent control of your diabetes and weight. This is 5 dollars/month!!!!
Add up the cost of your medications/month and then add on the potential dangerous or deadly side effects to your medications.
It’s up to you to take good care of your body. If you don’t treat the root problem of type 2 diabetes, medications just become very expensive and potentially dangerous Band-Aids. Let’s KISS…Keep It Safe and Simple when it comes to treating our body right!